[8] Martens CR, Denman BA, Mazzo MR, Armstrong ML, Reisdorph N, McQueen MB, Chonchol M, Seals DR
Whats Next: Regulatory filing for weight management: by end of 2025 Submission for type 2 diabetes: expected in 2026 Drug discovered by Chugai, licensed by Lilly in 2018 Implication: Orforglipron could become the first once-daily oral GLP-1 therapy with potent glucose-lowering and weight-loss benefits, potentially disrupting the injectable incretin market.
Here's something you might not know: most of the spermatozoa that leave the testes are actually infertile, 16 only becoming fertile after undergoing several biochemical processes while they cross the male and female genital tracts
The Phase 2 liver data showing 82% fat reduction provides strong rationale, but the Phase 3 endpoints are more demanding
Parlett, L., et
All this information will help them determine the most suitable course of medication management